Prof. López-Miranda major research interests focus on the dietary and genetics factors predisposing to cardiovascular disease, metabolic disease and their interaction with the environment and behavioral factors with special emphasis on diet and particularly on the gene-diet interaction determining cholesterol levels, insulin resistance, metabolic syndrome, obesity, endothelial function and cardiovascular diseases. The research carried out by his Unit is primarily in the area of human nutrition, personalized nutrition and the interaction between gene polymorphism and diet in lipoprotein metabolism, postprandial metabolism, insulin sensitivity, obesity, cardiovascular diseases and Metabolic Syndrome.