Personalized Prevention of Atherosclerotic Cardiovascular Disease. A Global Journey from Discovery to Implementation by Prof. Stephen J. Nicholls
This is the 2023 Anitschkow lecture given by Professor Stephen Nicholls at the 91st EAS Congress.
Professor Nicholls is Director of Monash Heart and Professor of Cardiology and Inaugural Director of the Victorian Heart Institute at Monash University, Australia. He is President-elect of the Cardiac Society of Australia and New Zealand, President of the Australian Atherosclerosis Society and Founding Chair of the Asia Pacific Cardiometabolic Consortium.
In his state-of-the-art lecture, Professor Nicholls presented data on the HDL functionality and antiatherogenic role, as well as the effects of HDL on atheromatous plaque volume, in vivo. Subsequently, he discussed the effect of statins or their combination with antiPCSK9 maps on plaque volume and composition. He also discussed results from clinical trials of the CETP inhibitors, Omega-3 fatty acids and bempedoic acid and presented ongoing clinical studies on Lp(a) and antidiabetic drugs. At the end of his lecture, he discussed the possible usefulness of polygenic risk scores for more efficient and intensive patient treatment. It is a very important and comprehensive lecture you should not miss.To the Open Lecture by Prof. Stephen J. Nicholls