Ruth Loos is Vice Executive Director and Group Leader of the Novo Nordisk Foundation Center for Basic Metabolic Research (CBMR) at the University of Copenhagen, and part-time professor at the Icahn School of Medicine at Mount Sinai, NY. She has almost two decades of experience in researching the genetic causes of obesity. As a founding member of the GIANT (Genetic Investigation of ANTropometric traits) consortium, she has pioneered many of the large-scale gene-discovery efforts that have thus far identified more than 1,000 obesity-associated loci.
She has a particular interest in studying more refined adiposity phenotypes or composite phenotypes (of multiple adiposity-related traits) to reveal new biology that has not been uncovered by traditional obesity outcomes. Ruth collaborates with bioinformaticians, molecular biologists and physiologists to bridge the translation gap from variant to function.
As more and more GWAS loci are being discovered, she examines whether genotype information can be used to identify subtypes of obesity, to predict who is at risk of becoming obese or to prescribe tailored prevention and treatment strategies in the context of precision diagnosis, prevention, and treatment.